Abnormal colposcopic findings: miscellaneous

Abstract

Colposcopic findings classified as “miscellaneous” are nonspecific alterations that may mimic high-grade lesions and hinder diagnosis, requiring clinical experience and correlation with cytological and virological data. These include atrophic epithelium, common in postmenopausal women and better evaluated after estrogen replacement; immature squamous metaplasia, with poorly defined acetowhite areas; and cervical inflammations, which alter the epithelium and should be treated before a new colposcopic examination. Leukoplakia, associated with HPV or chronic inflammation, requires biopsy, especially in the transformation zone. Post-treatment regeneration may present benign fine mosaic patterns. Proper use of acetic acid and Lugol’s iodine is essential, and the International Federation of Cervical Pathology and Colposcopy (IFCPC) recommends biopsy or follow-up in doubtful cases.